KCS or “dry eye” is an eye disease caused by abnormal tear production. A
deficiency in the lacrimal glands’ production of tears causes KCS in bulldogs.
Normal tears are essential for the health and transparency of the cornea (the
surface of the eye). Tears cleanse and lubricate the cornea, carry nutrients, and
play a role in the control of infection and in healing. Deficient tear production,
as in KCS, causes chronic irritation of the cornea and conjunctiva. Corneal
ulcers and eventually corneal scarring occur, and blindness can result.
KCS can occur as a result of viral infection, inflammation, drug-related toxicity,
or immune-mediated disease. There is an association between removal of a
cherry eye and the development of KCS.